Effect of Plumbagin on growth inhibition and apoptosis of imatinib-resistant chronic myeloid leukemia

Development of a new inhibitor of BCR-ABL tyrosine kinase is necessary for the treatment of chronic myeloid leukemia (CML) because of increasing resistance and tolerance to Imatinid efforts. Herein, we reported Plumbagin can significantly inhibit the growth of CML. The results revealed that Plumbag...

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Bibliographic Details
Main Authors: Bui Thi Kim Ly, Hoang Thanh Chi, Quach Ngo Diem Phuong, Ho Bao Thuy Quyen
Format: Article
Language:English
Published: HO CHI MINH CITY OPEN UNIVERSITY JOURNAL OF SCIENCE 2017-08-01
Series:Ho Chi Minh City Open University Journal of Science - Engineering and Technology
Subjects:
cml
Online Access:https://journalofscience.ou.edu.vn/index.php/tech-en/article/view/366