Alleviation of acute radiation-induced bone marrow failure in mice with human fetal placental stromal cell therapy

Alleviation of acute radiation-induced bone marrow failure in mice with human fetal placental stromal cell therapy

Abstract Purpose Selected placental mesenchymal stromal cells isolated from the fetal mesenchymal placental tissues (f-hPSCs) were tested as cell therapy of lethal acute radiation syndrome (ARS) with bone marrow regeneration and induced extramedullary hematopoiesis. Methods and materials f-hPSCs wer...

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Bibliographic Details
Main Authors: Evgenia Volinsky, Astar Lazmi-Hailu, Nerel Cohen, Boaz Adani, Mohammad Faroja, Myriam Grunewald, Raphael Gorodetsky
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Stem Cell Research & Therapy
Subjects:
Acute radiation syndrome (ARS)
Fetal human placental stromal cells (f-hPSCs)
Hematopoiesis
Hematopoietic stem cells (HSC)
Extra-medullary hematopoiesis (EMH)
Bone marrow
Online Access:http://link.springer.com/article/10.1186/s13287-020-01850-0

Internet

http://link.springer.com/article/10.1186/s13287-020-01850-0

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