Development and characterization of recombinant ovine coagulation factor VIII.

Animal models of the bleeding disorder, hemophilia A, have been an integral component of the biopharmaceutical development process and have facilitated the development of recombinant coagulation factor VIII (fVIII) products capable of restoring median survival of persons with hemophilia A to that of...

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Bibliographic Details
Main Authors: Philip M Zakas, Bagirath Gangadharan, Graca Almeida-Porada, Christopher D Porada, H Trent Spencer, Christopher B Doering
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3494657?pdf=render