Senolytics and senostatics as adjuvant tumour therapy
Cell senescence is a driver of ageing, frailty, age-associated disease and functional decline. In oncology, tumour cell senescence may contribute to the effect of adjuvant therapies, as it blocks tumour growth. However, this is frequently incomplete, and tumour cells that recover from senescence may...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-03-01
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Series: | EBioMedicine |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352396419300623 |