Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex

Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex

The yeast THO complex is recruited to active genes and interacts with the RNA-dependent ATPase Sub2 to facilitate the formation of mature export-competent messenger ribonucleoprotein particles and to prevent the co-transcriptional formation of RNA:DNA-hybrid-containing structures. How THO-containing...

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Bibliographic Details
Main Authors: Sandra K Schuller, Jan M Schuller, J Rajan Prabu, Marc Baumgärtner, Fabien Bonneau, Jérôme Basquin, Elena Conti
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-11-01
Series:eLife
Subjects:
RNA
helicase
R-loops
CryoEM
RNA export
transcription
Online Access:https://elifesciences.org/articles/61467

Internet

https://elifesciences.org/articles/61467

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