ADAM17 Promotes Motility, Invasion, and Sprouting of Lymphatic Endothelial Cells.

Tumor-associated lymphatic vessels actively participate in tumor progression and dissemination. ADAM17, a sheddase for numerous growth factors, cytokines, receptors, and cell adhesion molecules, is believed to promote tumor development, facilitating both tumor cell proliferation and migration, as we...

Full description

Bibliographic Details
Main Authors: Renata Mężyk-Kopeć, Barbara Wyroba, Krystyna Stalińska, Tomasz Próchnicki, Karolina Wiatrowska, Witold W Kilarski, Melody A Swartz, Joanna Bereta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4503755?pdf=render