IL-12 RB1 genetic variants contribute to human susceptibility to severe acute respiratory syndrome infection among Chinese.

BACKGROUND: Cytokines play important roles in antiviral action. We examined whether polymorphisms of interleukin (IL)-12 receptor B1 (IL-12RB1) affect the susceptibility to and outcome of severe acute respiratory syndrome (SARS). METHODS: A case-control study was carried out in Chinese SARS patients...

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Bibliographic Details
Main Authors: Fang Tang, Wei Liu, Fang Zhang, Zhong-Tao Xin, Mao-Ti Wei, Pan-He Zhang, Hong Yang, Hinh Ly, Wu-Chun Cao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2367437?pdf=render