Plumbagin suppresses the migration and invasion of glioma cells via downregulation of MMP-2/9 expression and inaction of PI3K/Akt signaling pathway in vitro

Plumbagin is a natural naphthoquinone constituent isolated from the roots of medicinal plant Plumbago zeylanica L., and has demonstrated anti-proliferative and anti-invasion activities in various cancer cells. However, its effect on the migration and invasion of glioma cells has not been elucidated....

Full description

Bibliographic Details
Main Authors: Guanghui Chen, Yan Yue, Jun Qin, Xinping Xiao, Qing Ren, Bin Xiao
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Journal of Pharmacological Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861317300609