Vitamin and antioxidant rich diet increases <it>MLH1</it> promoter DNA methylation in DMT2 subjects

<p>Abstract</p> <p>Background</p> <p>Oxidative stress may lead to an increased level of unrepaired cellular DNA damage, which is discussed as one risk for tumor initiation. Mismatch repair (MMR) enzymes act as proofreading complexes that maintain the genomic integrity a...

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Bibliographic Details
Main Authors: Switzeny Olivier J, Müllner Elisabeth, Wagner Karl-Heinz, Brath Helmut, Aumüller Eva, Haslberger Alexander G
Format: Article
Language:English
Published: BMC 2012-10-01
Series:Clinical Epigenetics
Subjects:
ROS
Online Access:http://www.clinicalepigeneticsjournal.com/content/4/1/19