Transport of thyroid hormones via the choroid plexus into the brain: the roles of transthyretin and thyroid hormone transporters

Transport of thyroid hormones via the choroid plexus into the brain: the roles of transthyretin and thyroid hormone transporters

Thyroid hormones (THs) are key players in regulating brain development. In humans, insufficient THs during gestation can lead to cretinism and mental retardation. Thus, transfer of appropriate quantities of THs from the blood into the brain at specific stages of development is critical.The choroid p...

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Bibliographic Details
Main Authors: Samantha J. Richardson, Roshen C. Wijayagunaratne, Damian G. D'Souza, Veerle M. Darras, Stijn L. J. Van Herck
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Neuroscience
Subjects:
Brain
Choroid Plexus
Thyroid Hormones
development
Blood-cerebrospinal fluid barrier
Thyroid hormone transporter
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2015.00066/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnins.2015.00066/full

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