Assembly of Nsp1 nucleoporins provides insight into nuclear pore complex gating.
Nuclear pore complexes (NPCs) form gateways for material transfer across the nuclear envelope of eukaryotic cells. Disordered proteins, rich in phenylalanine-glycine repeat motifs (FG-nups), form the central transport channel. Understanding how nups are arranged in the interior of the NPC may explai...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-03-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC3952814?pdf=render |