Assembly of Nsp1 nucleoporins provides insight into nuclear pore complex gating.

Nuclear pore complexes (NPCs) form gateways for material transfer across the nuclear envelope of eukaryotic cells. Disordered proteins, rich in phenylalanine-glycine repeat motifs (FG-nups), form the central transport channel. Understanding how nups are arranged in the interior of the NPC may explai...

Full description

Bibliographic Details
Main Authors: Ramya Gamini, Wei Han, John E Stone, Klaus Schulten
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-03-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3952814?pdf=render