Inter-dependent apical microtubule and actin dynamics orchestrate centrosome retention and neuronal delamination

Detachment of newborn neurons from the neuroepithelium is required for correct neuronal architecture and functional circuitry. This process, also known as delamination, involves adherens-junction disassembly and acto-myosin-mediated abscission, during which the centrosome is retained while apical/ci...

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Bibliographic Details
Main Authors: Ioannis Kasioulis, Raman M Das, Kate G Storey
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-10-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/26215