Glycine Regulates Neural Stem Cell Proliferation During Development via Lnx1-Dependent Notch Signaling

Glycine Regulates Neural Stem Cell Proliferation During Development via Lnx1-Dependent Notch Signaling

During development of the zebrafish embryo, glycine signaling promotes the differentiation of neural stem cells (NSCs). We found that glycine signaling suppresses the expression of Ligand of Numb X1 (lnx1, Ligand of numb protein-x1), a gene of unknown function during NSC differentiation that is sele...

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Bibliographic Details
Main Authors: Abdelhamid Bekri, Meijiang Liao, Pierre Drapeau
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Molecular Neuroscience
Subjects:
LNX1
NSCs
glycine signaling
neurogenesis
Notch activity
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2019.00044/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2019.00044/full

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