Design and evaluation of rhubarb total free anthraquinones oral colon-specific drug delivery granules to improve the purgative effect

Rhubarb is commonly used as a cathartic in Asian countries. However, researchers have devotedextensive concerns to the quality control and safety of rhubarb and traditional Chinese preparations composed of rhubarb due to the instable purgative effect and potential nephrotoxicity of anthraquinones. I...

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Bibliographic Details
Main Authors: Hongwei Wei, Jinhua Chang, Pei Liu, Zhongsi Li, Guangxin Miao, Xigang Liu, Cuizhe Liu, Xiangrong Zhang
Format: Article
Language:English
Published: Universidade de São Paulo
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100500&lng=en&tlng=en