CD10 marks non-canonical PPARγ-independent adipocyte maturation and browning potential of adipose-derived stem cells

CD10 marks non-canonical PPARγ-independent adipocyte maturation and browning potential of adipose-derived stem cells

Abstract Background Effective stem cell therapy is dependent on the stem cell quality that is determined by their differentiation potential, impairment of which leads to poor engraftment and survival into the target cells. However, limitations in our understanding and the lack of reliable markers th...

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Bibliographic Details
Main Authors: Smarajit Chakraborty, Wee Kiat Ong, Winifred W. Y. Yau, Zhihong Zhou, K. N. Bhanu Prakash, Sue-Anne Toh, Weiping Han, Paul M. Yen, Shigeki Sugii
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Stem Cell Research & Therapy
Subjects:
Biomarker, adipogenesis
Quality, adipose-derived mesenchymal stem cells
Adipocytes, beige
Adipocytes, non-canonical activation
Lipolytic pathways
Seahorse analysis, oxidative metabolism
Online Access:https://doi.org/10.1186/s13287-021-02179-y

Internet

https://doi.org/10.1186/s13287-021-02179-y

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