A Study of Morphological Changes in Renal Afferent Arterioles Induced by Angiotensin II Type 1 Receptor Blockers in Hypertensive Patients

Background: Renin-angiotensin-aldosterone system blockers are known to reduce hypertrophy of vascular smooth muscle cells (SMCs) in hypertensive cases. However, we have reported marked proliferative changes of renal afferent arteriolar SMCs in rats induced by a long-term administration of angiotensi...

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Main Authors: Yohko Nagai, Fumito Yamabe, Yosuke Sasaki, Takamasa Ishii, Kazushige Nakanishi, Koichi Nakajima, Kazutoshi Shibuya, Tetsuo Mikami, Yoshikiyo Akasaka, Yoshihisa Urita, Nobuaki Yamanaka
Format: Article
Language:English
Published: Karger Publishers 2020-01-01
Series:Kidney & Blood Pressure Research
Subjects:
Online Access:https://www.karger.com/Article/FullText/505025