Mixed Hypertrophic and Dilated Phenotype of Cardiomyopathy in a Patient With Homozygous In-Frame Deletion in the MyBPC3 Gene Treated as Myocarditis for a Long Time

Mixed Hypertrophic and Dilated Phenotype of Cardiomyopathy in a Patient With Homozygous In-Frame Deletion in the MyBPC3 Gene Treated as Myocarditis for a Long Time

Hypertrophic cardiomyopathy (HCM) is the most common inherited disease, with a prevalence of 1:200 worldwide. The cause of HCM usually presents with an autosomal dominant mutation in the genes encoding one of more than 20 sarcomeric proteins, incomplete penetrance, and variable expressivity. HCM cla...

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Bibliographic Details
Main Authors: Olga Blagova, Indira Alieva, Eugenia Kogan, Alexander Zaytsev, Vsevolod Sedov, S. Chernyavskiy, Yulia Surikova, Ilya Kotov, Elena V. Zaklyazminskaya
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Pharmacology
Subjects:
hypertrophic cardiomyopathy
dilated cardiomyopathy
MyBPC3 gene
heart failure progression
bi-allelic mutations
myocarditis
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.579450/full

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https://www.frontiersin.org/article/10.3389/fphar.2020.579450/full

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