PDK1 Is a Regulator of Epidermal Differentiation that Activates and Organizes Asymmetric Cell Division

PDK1 Is a Regulator of Epidermal Differentiation that Activates and Organizes Asymmetric Cell Division

Asymmetric cell division (ACD) in a perpendicular orientation promotes cell differentiation and organizes the stratified epithelium. However, the upstream cues regulating ACD have not been identified. Here, we report that phosphoinositide-dependent kinase 1 (PDK1) plays a critical role in establishi...

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Bibliographic Details
Main Authors: Teruki Dainichi, Matthew S. Hayden, Sung-Gyoo Park, Hyunju Oh, John J. Seeley, Yenkel Grinberg-Bleyer, Kristen M. Beck, Yoshiki Miyachi, Kenji Kabashima, Takashi Hashimoto, Sankar Ghosh
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716304788

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http://www.sciencedirect.com/science/article/pii/S2211124716304788

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