Ezrin Is a Novel Protein Partner of Aquaporin-5 in Human Salivary Glands and Shows Altered Expression and Cellular Localization in Sjögren’s Syndrome

Ezrin Is a Novel Protein Partner of Aquaporin-5 in Human Salivary Glands and Shows Altered Expression and Cellular Localization in Sjögren’s Syndrome

Sjögren’s syndrome (SS) is an exocrinopathy characterized by the hypofunction of salivary glands (SGs). Aquaporin-5 (AQP5); a water channel involved in saliva formation; is aberrantly distributed in SS SG acini and contributes to glandular dysfunction. We aimed to investigate the role of ezrin in AQ...

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Bibliographic Details
Main Authors: Clara Chivasso, Carl Johan Hagströmer, Kristie L. Rose, Florent Lhotellerie, Lionel Leblanc, Zhen Wang, Stefania Moscato, Clément Chevalier, Egor Zindy, Maud Martin, Benoit Vanhollebeke, Françoise Gregoire, Nargis Bolaky, Jason Perret, Chiara Baldini, Muhammad Shahnawaz Soyfoo, Letizia Mattii, Kevin L. Schey, Susanna Törnroth-Horsefield, Christine Delporte
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
Sjögren’s syndrome
aquaporin-5
ezrin
salivary glands
protein–protein interaction
Online Access:https://www.mdpi.com/1422-0067/22/17/9213

Internet

https://www.mdpi.com/1422-0067/22/17/9213

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