Correction of hypoalphalipoproteinemia in LDL receptor-deficient rabbits by lecithin:cholesterol acyltransferase

Correction of hypoalphalipoproteinemia in LDL receptor-deficient rabbits by lecithin:cholesterol acyltransferase

Familial hypercholesterolemia (FH), a disease caused by a variety of mutations in the low density lipoprotein receptor (LDLr) gene, leads not only to elevated LDL-cholesterol (C) concentrations but to reduced high density lipoprotein (HDL)-C and apolipoprotein (apo) A-I concentrations as well. The r...

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Bibliographic Details
Main Authors: Margaret E. Brousseau, Jian Wang, Stephen J. Demosky, Jr., Boris L. Vaisman, Glenda D. Talley, Silvia Santamarina-Fojo, H. Bryan Brewer, Jr., Jeffrey M. Hoeg
Format: Article
Language:English
Published: Elsevier 1998-08-01
Series:Journal of Lipid Research
Subjects:
familial hypercholesterolemia
high density lipoproteins
apolipoprotein A-I
metabolism
lecithin:cholesterol acyltransferase
WHHL rabbit
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520321842

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http://www.sciencedirect.com/science/article/pii/S0022227520321842

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