Cerebrospinal Fluid IgM Levels in Association With Inflammatory Pathways in Multiple Sclerosis Patients

Cerebrospinal Fluid IgM Levels in Association With Inflammatory Pathways in Multiple Sclerosis Patients

BackgroundIntrathecal immunoglobulin M (IgM) synthesis has been demonstrated in the early disease stages of multiple sclerosis (MS) as a predictor factor of a worsening disease course. Similarly, increased cerebrospinal fluid (CSF) molecules related to B-cell intrathecal activity have been associate...

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Bibliographic Details
Main Authors: Roberta Magliozzi, Valentina Mazziotti, Luigi Montibeller, Anna I. Pisani, Damiano Marastoni, Agnese Tamanti, Stefania Rossi, Francesco Crescenzo, Massimiliano Calabrese
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Cellular Neuroscience
Subjects:
CSF
multiple sclerosis
B cell
lesion activity
immunoglobulin M
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2020.569827/full

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https://www.frontiersin.org/article/10.3389/fncel.2020.569827/full

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