Molecular Determinants of Cancer Therapy Resistance to HDAC Inhibitor-Induced Autophagy

Histone deacetylation inhibitors (HDACi) offer high potential for future cancer therapy as they can re-establish the expression of epigenetically silenced cell death programs. HDACi-induced autophagy offers the possibility to counteract the frequently present apoptosis-resistance as well as stress c...

Full description

Bibliographic Details
Main Authors: Maria Mrakovcic, Leopold F. Fröhlich
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/1/109