EGFR Interacts with the Fusion Protein of Respiratory Syncytial Virus Strain 2-20 and Mediates Infection and Mucin Expression.

EGFR Interacts with the Fusion Protein of Respiratory Syncytial Virus Strain 2-20 and Mediates Infection and Mucin Expression.

Respiratory syncytial virus (RSV) is the major cause of viral lower respiratory tract illness in children. In contrast to the RSV prototypic strain A2, clinical isolate RSV 2-20 induces airway mucin expression in mice, a clinically relevant phenotype dependent on the fusion (F) protein of the RSV st...

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Bibliographic Details
Main Authors: Michael G Currier, Sujin Lee, Christopher C Stobart, Anne L Hotard, Remi Villenave, Jia Meng, Carla D Pretto, Michael D Shields, Minh Trang Nguyen, Sean O Todd, Michael H Chi, Jason Hammonds, Stefanie A Krumm, Paul Spearman, Richard K Plemper, Kaori Sakamoto, R Stokes Peebles, Ultan F Power, Martin L Moore
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-05-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4859522?pdf=render

Internet

http://europepmc.org/articles/PMC4859522?pdf=render

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