Quercetin Attenuates Manganese-Induced Neuroinflammation by Alleviating Oxidative Stress through Regulation of Apoptosis, iNOS/NF-κB and HO-1/Nrf2 Pathways

Quercetin Attenuates Manganese-Induced Neuroinflammation by Alleviating Oxidative Stress through Regulation of Apoptosis, iNOS/NF-κB and HO-1/Nrf2 Pathways

Manganese (Mn) is an essential trace element required for the development of human body and acts as an enzyme co-factor or activator for various reactions of metabolism. While essential in trace amounts, excessive Mn exposure can result in toxic accumulations in human brain tissue and resulting extr...

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Bibliographic Details
Main Authors: Entaz Bahar, Ji-Ye Kim, Hyonok Yoon
Format: Article
Language:English
Published: MDPI AG 2017-09-01
Series:International Journal of Molecular Sciences
Subjects:
manganese
manganism
quercetin
oxidative stress
neuroinflammation
apoptosis
Online Access:https://www.mdpi.com/1422-0067/18/9/1989

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https://www.mdpi.com/1422-0067/18/9/1989

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