The Local Anesthetic Bupivacaine Inhibits the Progression of Non-Small Cell Lung Cancer by Inducing Autophagy Through Akt/mTOR Signaling

The Local Anesthetic Bupivacaine Inhibits the Progression of Non-Small Cell Lung Cancer by Inducing Autophagy Through Akt/mTOR Signaling

Non-small cell lung cancer (NSCLC) is a prevalent malignancy with high mortality and poor prognosis. Bupivacaine serves as a widely used local anesthetic and presents potential anti-tumor activity. Nevertheless, the function of bupivacaine in the NSCLC development remains elusive. Here, we tried to...

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Bibliographic Details
Main Authors: Jian-Hua Gu, Cui-Cui Liu, Jin-Lan Xie, Bin Ma, Shao-Min Cui, Guang-Zhu Yang, Shun-Cheng He
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oncology
Subjects:
NSCLC
progression
bupivacaine
autophagy
Akt/mTOR signaling
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.616445/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.616445/full

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