The Role of the Insulin-Like Growth Factor 1 Pathway in Immune Tumor Microenvironment and Its Clinical Ramifications in Gynecologic Malignancies

The Role of the Insulin-Like Growth Factor 1 Pathway in Immune Tumor Microenvironment and Its Clinical Ramifications in Gynecologic Malignancies

Treatment of patients with gynecologic malignancies diagnosed at advanced stages remains a therapeutic challenge. Survival rates of these patients remain significantly low, despite surgery and chemotherapy. Advances in understanding the role of the immune system in the pathogenesis of cancer have le...

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Bibliographic Details
Main Authors: Muna Alemi Yahya, Shilhav Meisel Sharon, Shay Hantisteanu, Mordechai Hallak, Ilan Bruchim
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Endocrinology
Subjects:
immunotherapy
ovarian cancer
cervical cancer
endometrial cancer
gynecologic cancers
insulin-like growth factor 1 pathway
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00297/full

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https://www.frontiersin.org/article/10.3389/fendo.2018.00297/full

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