CD44 Promotes intoxication by the clostridial iota-family toxins.

CD44 Promotes intoxication by the clostridial iota-family toxins.

Various pathogenic clostridia produce binary protein toxins associated with enteric diseases of humans and animals. Separate binding/translocation (B) components bind to a protein receptor on the cell surface, assemble with enzymatic (A) component(s), and mediate endocytosis of the toxin complex. Ul...

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Bibliographic Details
Main Authors: Darran J Wigelsworth, Gordon Ruthel, Leonie Schnell, Peter Herrlich, Josip Blonder, Timothy D Veenstra, Robert J Carman, Tracy D Wilkins, Guy Tran Van Nhieu, Serge Pauillac, Maryse Gibert, Nathalie Sauvonnet, Bradley G Stiles, Michel R Popoff, Holger Barth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3517468?pdf=render

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http://europepmc.org/articles/PMC3517468?pdf=render

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