The Role of IL-1β in the Bone Loss during Rheumatic Diseases

Several inflammatory diseases have been associated with increased bone resorption and fracture rates and different studies supported the relation between inflammatory cytokines and osteoclast activity. The main factor required for osteoclast activation is the stimulation by receptor activator of nuc...

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Bibliographic Details
Main Authors: Piero Ruscitti, Paola Cipriani, Francesco Carubbi, Vasiliki Liakouli, Francesca Zazzeroni, Paola Di Benedetto, Onorina Berardicurti, Edoardo Alesse, Roberto Giacomelli
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2015/782382