Social defeat-induced anhedonia: effects on operant sucrose-seeking behavior

Reduced capacity to experience pleasure, also known as anhedonia, is a key feature of the depressive state and is associated with poor disease prognosis and treatment outcome. Various behavioral readouts (e.g. reduced sucrose intake) have been employed in animal models of depression as a measure of...

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Bibliographic Details
Main Authors: Danai eRiga, J. Trisna Theijs, Taco J De Vries, August B Smit, Sabine eSpijker
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-08-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2015.00195/full