Characterization of a Novel CYP2C9 Mutation (1009C>A) Detected in a Warfarin-Sensitive Patient

Characterization of a Novel CYP2C9 Mutation (1009C>A) Detected in a Warfarin-Sensitive Patient

Abstract.: Warfarin is the most frequently prescribed anticoagulant for the long-term treatment in the clinic. Recent studies have shown that polymorphic alleles within the CYP2C9, VKORC1, and CYP4F2 genes are related to the warfarin dosage requirement. In this study, a novel nonsynonymous mutation...

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Main Authors: Shun-Bin Luo, Chuan-Bao Li, Da-Peng Dai, Shuang-Hu Wang, Zhen-He Wang, Pei-Wu Geng, Jie Cai, Zhe-Li Jiang, Cheng-Wei Pu, Ke Shang, Xin-Min Yuan, Ya-Po Cao, Guo-Xin Hu, Jian-Ping Cai
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319301379

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http://www.sciencedirect.com/science/article/pii/S1347861319301379

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