Mac-1 directly binds to the endothelial protein C-receptor: a link between the protein C anticoagulant pathway and inflammation?

Mac-1 directly binds to the endothelial protein C-receptor: a link between the protein C anticoagulant pathway and inflammation?

OBJECTIVE: The endothelial protein C-receptor (EPCR) is an endothelial transmembrane protein that binds protein C and activated protein C (APC) with equal affinity, thereby facilitating APC formation. APC has anticoagulant, antiapoptotic and antiinflammatory properties. Soluble EPCR, released by the...

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Bibliographic Details
Main Authors: Katrin Fink, Hans-Jörg Busch, Natascha Bourgeois, Meike Schwarz, Dennis Wolf, Andreas Zirlik, Karlheinz Peter, Christoph Bode, Constantin von Zur Muhlen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3567096?pdf=render

Internet

http://europepmc.org/articles/PMC3567096?pdf=render

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