Novel protease inhibitors active against human neutrophil elastase and plasma kallikrein with therapeutic potentialities: Structure-function relationships

Novel protease inhibitors active against human neutrophil elastase and plasma kallikrein with therapeutic potentialities: Structure-function relationships

Two new protease inhibitors (PIs), CmPI-II and AdKI were purified and characterized from mollusks Cenchritis muricatus and Aplysia dactylomela, respectively. They showed different specificities, CmPI-II for human neutrophil elastase (HNE) and AdKI for human plasma kallikrein (HPK). Purification proc...

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Bibliographic Details
Main Authors: Yamile González González, Dayrom Gil, Maday Alonso del Rivero, Vladimir Besada, Jeovanis Gil, Mariana S Araujo, Aparecida S Tanaka, Tirso Pons, María de los Angeles Chávez
Format: Article
Language:English
Published: Elfos Scientiae
Series:Biotecnología Aplicada
Subjects:
inhibitor
protease
marine invertebrates
mollusk
Online Access:http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1027-28522010000400009&lng=en&tlng=en

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http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1027-28522010000400009&lng=en&tlng=en

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