Neuropeptide Y Stimulates Proliferation and Migration of Vascular Smooth Muscle Cells from Pregnancy Hypertensive Rats via Y1 and Y5 Receptors.

The increased proliferation and migration of vascular smooth muscle cells (VSMCs) play important roles in pathophysiological remodeling of arteries during hypertension in pregnancy. However, the mechanisms involved in this process remain unclear. We hypothesized that Neuropeptide Y (NPY), which is a...

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Bibliographic Details
Main Authors: Ping Zhang, Ying-Xin Qi, Qing-Ping Yao, Xiao-Hu Chen, Guo-Liang Wang, Bao-Rong Shen, Yue Han, Li-Zhi Gao, Zong-Lai Jiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0131124