An integrated mass-spectrometry pipeline identifies novel protein coding-regions in the human genome.
Most protein mass spectrometry (MS) experiments rely on searches against a database of known or predicted proteins, limiting their ability as a gene discovery tool.Using a search against an in silico translation of the entire human genome, combined with a series of annotation filters, we identified...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2010-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC2812506?pdf=render |