Tumor Microenvironment Cascade-Responsive Nanodrug with Self-Targeting Activation and ROS Regeneration for Synergistic Oxidation-Chemotherapy

Tumor Microenvironment Cascade-Responsive Nanodrug with Self-Targeting Activation and ROS Regeneration for Synergistic Oxidation-Chemotherapy

Abstract Carrier-free nanodrug with exceptionally high drug payload has attracted increasing attentions. Herein, we construct a pH/ROS cascade-responsive nanodrug which could achieve tumor acidity-triggered targeting activation followed by circularly amplified ROS-triggered drug release via positive...

Full description

Bibliographic Details
Main Authors: Yang Li, Jinyan Lin, Peiyuan Wang, Qiang Luo, Fukai Zhu, Yun Zhang, Zhenqing Hou, Xiaolong Liu, Jingfeng Liu
Format: Article
Language:English
Published: SpringerOpen 2020-09-01
Series:Nano-Micro Letters
Subjects:
Targeting activation
Positive-feedback loop
Circular amplification of ROS
Vitamin E nanodrug
Synergistic oxidation-chemotherapy
Online Access:http://link.springer.com/article/10.1007/s40820-020-00492-4

Internet

http://link.springer.com/article/10.1007/s40820-020-00492-4

Similar Items