Deciphering the Molecular Mechanism of Spontaneous Senescence in Primary Epithelial Ovarian Cancer Cells

Deciphering the Molecular Mechanism of Spontaneous Senescence in Primary Epithelial Ovarian Cancer Cells

Spontaneous senescence of cancer cells remains a puzzling and poorly understood phenomenon. Here we comprehensively characterize this process in primary epithelial ovarian cancer cells (pEOCs). Analysis of tumors from ovarian cancer patients showed an abundance of senescent cells in vivo. Further, s...

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Bibliographic Details
Main Authors: Martyna Pakuła, Ewa Mały, Paweł Uruski, Anna Witucka, Małgorzata Bogucka, Natalia Jaroszewska, Nicoletta Makowska, Arkadiusz Niklas, Rafał Moszyński, Stefan Sajdak, Andrzej Tykarski, Justyna Mikuła-Pietrasik, Krzysztof Książek
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cancers
Subjects:
aging biomarkers
cancer biology
cellular senescence
epithelial ovarian cancer
oxidative stress
Online Access:https://www.mdpi.com/2072-6694/12/2/296

Internet

https://www.mdpi.com/2072-6694/12/2/296

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