Wt-1 Expression Linked to Nitric Oxide Availability during Neonatal Obstructive Nephropathy

The wt-1 gene encodes a zinc finger DNA-binding protein that acts as a transcriptional activator or repressor depending on the cellular or chromosomal context. The wt-1 regulates the expression of a large number of genes that have a critical role in kidney development. Congenital obstructive nephrop...

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Bibliographic Details
Main Authors: Luciana Mazzei, Walter Manucha
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Advances in Urology
Online Access:http://dx.doi.org/10.1155/2013/401750