Noise cancellation using total variation for copy number variation detection
Abstract Background Due to recent advances in sequencing technologies, sequence-based analysis has been widely applied to detecting copy number variations (CNVs). There are several techniques for identifying CNVs using next generation sequencing (NGS) data, however methods employing depth of coverag...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-10-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12859-018-2332-x |