Human Metapneumovirus Establishes Persistent Infection in Lung Microvascular Endothelial Cells and Primes a Th2-Skewed Immune Response

Human Metapneumovirus Establishes Persistent Infection in Lung Microvascular Endothelial Cells and Primes a Th2-Skewed Immune Response

<i>Human Metapneumovirus</i> (HMPV) is a major cause of lower respiratory tract infections. HMPV infection has been hypothesized to alter dendritic cell (DC) immune response; however, many questions regarding HMPV pathogenesis within the infected lung remain unanswered. Here, we show tha...

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Bibliographic Details
Main Authors: Antonella Bugatti, Stefania Marsico, Manuela Fogli, Sara Roversi, Serena Messali, Daniela Bosisio, Cinzia Giagulli, Arnaldo Caruso, Silvano Sozzani, Simona Fiorentini, Francesca Caccuri
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Microorganisms
Subjects:
<i>human metapneumovirus</i>
dendritic cells
Th2 response
IL-4
OX40L
Online Access:https://www.mdpi.com/2076-2607/8/6/824

Internet

https://www.mdpi.com/2076-2607/8/6/824

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