Glucose metabolism involved in PD-L1-mediated immune escape in the malignant kidney tumour microenvironment

Abstract Programmed death receptor-ligand 1 (PD-L1) plays a crucial role in immune evasion by tumour cells. Most tumour cells exhibit energy dependency and acquire energy from glycolysis. However, the relationship between glucose metabolism and PD-L1 expression remains unclear. In this study, change...

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Bibliographic Details
Main Authors: Yongbo Yu, Ye Liang, Dan Li, Liping Wang, Zhijuan Liang, Yuanbin Chen, Guofeng Ma, Hui Wu, Wei Jiao, Haitao Niu
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-021-00401-7