CD97/ADGRE5 Inhibits LPS Induced NF-κB Activation through PPAR-γ Upregulation in Macrophages

CD97/ADGRE5 protein is predominantly expressed on leukocytes and belongs to the EGF-TM7 receptors family. It mediates granulocytes accumulation in the inflammatory tissues and is involved in firm adhesion of PMNC on activated endothelial cells. There have not been any studies exploring the role of C...

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Bibliographic Details
Main Authors: Shuai Wang, Zewei Sun, Wenting Zhao, Zhen Wang, Mingjie Wu, Yanyun Pan, Hui Yan, Jianhua Zhu
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2016/1605948