CD57(high) neuroblastoma cells have aggressive attributes ex situ and an undifferentiated phenotype in patients.

BACKGROUND: Neuroblastoma is thought to originate from neural crest-derived cells. CD57 defines migratory neural crest cells in normal development and is expressed in neuroblastoma. METHODOLOGY AND PRINCIPAL FINDINGS: We investigated the role of CD57 expression in neuroblastoma cells ex situ and in...

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Bibliographic Details
Main Authors: Anne-Marie Schlitter, Carmen Dorneburg, Thomas F E Barth, Joachim Wahl, Johannes H Schulte, Silke Brüderlein, Klaus-Michael Debatin, Christian Beltinger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3416815?pdf=render