Maturation and Phenotypic Heterogeneity of Human CD4+ Regulatory T Cells From Birth to Adulthood and After Allogeneic Stem Cell Transplantation

Maturation and Phenotypic Heterogeneity of Human CD4+ Regulatory T Cells From Birth to Adulthood and After Allogeneic Stem Cell Transplantation

CD4+ Regulatory T cells (Treg) play a critical role in maintaining immune homeostasis. Various Treg subsets have been identified, however the heterogeneity of Treg subpopulations during development remains uncharacterized. Using mass cytometry we obtained single cell data on expression of 35 functio...

Full description

Bibliographic Details
Main Authors: Tiago R. Matos, Masahiro Hirakawa, Ana C. Alho, Lars Neleman, Luis Graca, Jerome Ritz
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Immunology
Subjects:
Treg - regulatory T cell
immunology
T cell
heterogeneity
diversity
GvHD
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.570550/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.570550/full

Similar Items