Mind the replication gap

Unlike bacteria, mammalian cells need to complete DNA replication before segregating their chromosomes for the maintenance of genome integrity. Thus, cells have evolved efficient pathways to restore stalled and/or collapsed replication forks during S-phase, and when necessary, also to delay cell cyc...

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Bibliographic Details
Main Authors: Camelia Mocanu, Kok-Lung Chan
Format: Article
Language:English
Published: The Royal Society 2021-06-01
Series:Royal Society Open Science
Subjects:
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsos.201932