Mind the replication gap
Unlike bacteria, mammalian cells need to complete DNA replication before segregating their chromosomes for the maintenance of genome integrity. Thus, cells have evolved efficient pathways to restore stalled and/or collapsed replication forks during S-phase, and when necessary, also to delay cell cyc...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
The Royal Society
2021-06-01
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Series: | Royal Society Open Science |
Subjects: | |
Online Access: | https://royalsocietypublishing.org/doi/10.1098/rsos.201932 |