Unique CRF01_AE Gag CTL epitopes associated with lower HIV-viral load and delayed disease progression in a cohort of HIV-infected Thais.

Cytotoxic T Lymphocytes (CTLs) play a central role in controlling HIV-replication. Although numerous CTL epitopes have been described, most are in subtype B or C infection. Little is known about CTL responses in CRF01_AE infection. Gag CTL responses were investigated in a cohort of 137 treatment-naï...

Full description

Bibliographic Details
Main Authors: Masahiko Mori, Busarawan Sriwanthana, Nuanjun Wichukchinda, Chetsada Boonthimat, Naho Tsuchiya, Toshiyuki Miura, Panita Pathipvanich, Koya Ariyoshi, Pathom Sawanpanyalert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3149616?pdf=render