Clinical perspective on the use of human amniotic epithelial cells to treat congenital metabolic diseases with a focus on maple syrup urine disease

Abstract Congenital metabolic diseases are a group of hereditary disorders caused by the deficiency of a single specific enzyme activity. Without appropriate therapy, affected patients suffer severe neurologic disability and eventual death. The current mainstays of management attempt to slow disease...

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Bibliographic Details
Main Authors: Chika Takano, Brendan H. Grubbs, Mika Ishige, Erika Ogawa, Ichiro Morioka, Satoshi Hayakawa, Toshio Miki
Format: Article
Language:English
Published: Wiley 2021-06-01
Series:Stem Cells Translational Medicine
Subjects:
Online Access:https://doi.org/10.1002/sctm.20-0225