Enhanced oral bioavailability of [6]-Gingerol-SMEDDS: Preparation, in vitro and in vivo evaluation

Enhanced oral bioavailability of [6]-Gingerol-SMEDDS: Preparation, in vitro and in vivo evaluation

The purpose of this study was to develop a [6]-Gingerol-loaded self-microemulsifying drug delivery system ([6]-Gingerol-SMEDDS) for oral administration and enhanced bioavailability of the drug. The [6]-Gingerol-SMEDDS, consisting of oils (ethyl oleate), surfactant (Cremophor EL35) and co-surfactant...

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Bibliographic Details
Main Authors: Yang Xu, Qilong Wang, Yingshu Feng, Caleb Kesse Firempong, Yuan Zhu, Emmanuel Omari-Siaw, Yuanyuan Zheng, Zunqin Pu, Ximing Xu, Jiangnan Yu
Format: Article
Language:English
Published: Elsevier 2016-12-01
Series:Journal of Functional Foods
Subjects:
[6]-Gingerol
SMEDDS
In vitro release
Pharmacokinetics
Solubility
Bioavailability
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464616303206

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http://www.sciencedirect.com/science/article/pii/S1756464616303206

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