Navigating the crowd: visualizing coordination between genome dynamics, structure, and transcription

Abstract The eukaryotic genome is hierarchically structured yet highly dynamic. Regulating transcription in this environment demands a high level of coordination to permit many proteins to interact with chromatin fiber at appropriate sites in a timely manner. We describe how recent advances in quant...

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Bibliographic Details
Main Authors: Haitham A. Shaban, Roman Barth, Kerstin Bystricky
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Genome Biology
Online Access:http://link.springer.com/article/10.1186/s13059-020-02185-y