Metabolomics guided pathway analysis reveals link between cancer metastasis, cholesterol sulfate, and phospholipids

Metabolomics guided pathway analysis reveals link between cancer metastasis, cholesterol sulfate, and phospholipids

Abstract Background Cancer cells that enter the metastatic cascade require traits that allow them to survive within the circulation and colonize distant organ sites. As disseminating cancer cells adapt to their changing microenvironments, they also modify their metabolism and metabolite production....

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Bibliographic Details
Main Authors: Caroline H. Johnson, Antonio F. Santidrian, Sarah E. LeBoeuf, Michael E. Kurczy, Nicholas J. W. Rattray, Zahra Rattray, Benedikt Warth, Melissa Ritland, Linh T. Hoang, Celine Loriot, Jason Higa, James E. Hansen, Brunhilde H. Felding, Gary Siuzdak
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Cancer & Metabolism
Subjects:
Cancer
Cholesterol sulfate
Phospholipids
Autonomous metabolomics
Mummichog
Metastasis
Online Access:http://link.springer.com/article/10.1186/s40170-017-0171-2

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http://link.springer.com/article/10.1186/s40170-017-0171-2

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