Loading and Skeletal Development and Maintenance

Mechanical loading is a major regulator of bone mass and geometry. The osteocytes network is considered the main sensor of loads, through the shear stress generated by strain induced fluid flow in the lacuno-canalicular system. Intracellular transduction implies several kinases and phosphorylation o...

Full description

Bibliographic Details
Main Authors: P. Bergmann, J. J. Body, S. Boonen, Y. Boutsen, J. P. Devogelaer, S. Goemaere, J. Kaufman, J. Y. Reginster, S. Rozenberg
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Journal of Osteoporosis
Online Access:http://dx.doi.org/10.4061/2011/786752